Emil Vogt

Postdoctoral researcher

Center for Free-Electron Laser Science (CFEL)
Deutsches Elektronen-Synchrotron DESY
Notkestr. 85 (building 99a, room O3.010)
22607 Hamburg
Germany

CMI theory

emil.vogt@cfel.de

+49-40-8998 6307

Research

My research focuses on the theoretical rotational-vibrational spectroscopy and dynamics of small gas-phase molecules. As a member of the theory team in the Controlled Molecule Imaging group, I have contributed to the development of a new method for spectral calculations based on normalizing flows, invertible neural networks, that enable learnable coordinate transformations. I am currently exploring how these learned coordinates can be used to enhance conventional approaches for computing static molecular properties and molecular dynamics.

Curriculum Vitae

10/2024–present	Marie Skłodowska-Curie Actions Postdoctoral researcher at Center for Free Electron Laser Science, DESY, Hamburg, Germany
10/2023–09/2024	Postdoctoral researcher at Center for Free Electron Laser Science, DESY, Hamburg, Germany
04/2023–09/2023	Postdoctoral researcher at University of Copenhagen, Copenhagen, Denmark
10/2019–03/2023	PhD in Chemistry at University of Copenhagen, Copenhagen, Denmark

Publications

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Research team sheds light on the future potential of X-ray imaging and cryo-electron microscopy

09 May 2025

Scientists from DESY, CSSB, CUI, and Uppsala University publish groundbreaking review article.

Breakthrough in laser-alignment for macromolecular single-particle imaging

10 April 2025

Single-particle diffractive imaging (SPI) using X-ray free-electron lasers allows researchers to reconstruct the structure of nanoparticles and biomolecules. However, the technique often requires imaging up to several billion nanoparticles to produce the image and imposes limitations on its clarity and sharpness. Researchers at the Center for Free-Electron Laser Science at DESY, together with international colleagues, recently demonstrated that laser-induced alignment can indeed be achieved to significantly improve molecular imaging techniques. This geometric confinement of the molecules in the x-ray-imaging experiment will greatly facilitate the recovery of the molecular orientation and, therefore, the structure retrieval. It thus overcomes a significant challenge in single-particle diffractive imaging. This novel development further paves the way for solving the three-dimensional structures of proteins and other macromolecules using SPI.

Recent Publications